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Diagnostic Analyte to Enrich LINE-1 and Detect LINE-1 Driven Oncologic Disease

This invention is a biomarker model, in which the biomarker detected can be used as a companion diagnostic or for screening and diagnosis of a variety of cancers. The model includes a novel liquid biopsy process that accurately measures biomarkers from blood samples by enriching for cell-derived vesicles shed directly from affected tissues. The data...

Published: 11/16/2023 | Inventor(s): Kenneth Ramos, Emma Bowers, Patrick Silva, Brian Mckay

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Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers

Novel Biomarker for Diagnosis and Treatment of Chronic Lung Diseases

This invention is a targeted method of treating conditions associated with aberrant L1 expression, including cancers. The method involves determining the expression levels of L1 in a patient and then administering a known TGF-β1 inhibitor. Further, the invention acts on the discovery of an underlying mechanism of aberrant L1 expression that will...

Published: 11/16/2023 | Inventor(s): Kenneth Ramos, Elsa Reyes Reyes, Pasano Bojang, Patrick Silva

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Therapeutics