|
Inhibition of Exosome Secretion in Triple Negative Breast Cancer
This invention is a new anti-cancer peptide for treatment of Triple-Negative Breast Cancer (TNBC). This new peptide-based therapeutic focuses on blocking of Epidermal Growth Factor Receptor (EGFR) and SNX1. In addition, this peptide blocks the secretion of harmful exosomes that further cancer cell metastasis and modulate the immune environment.
Background:...
Published: 11/14/2024
|
Inventor(s): Joyce Schroeder, Ryan Hecksel, Abigail Camenisch, Delina Denogean, Josh Lederman
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Therapeutics
|
|
Peptide Therapeutic for Immune Response Activation against Metastatic Triple Negative Breast Cancer
This invention provides compositions and methods for treating triple negative breast cancer using peptides or peptide mimics that bind to epidermal growth factor receptor (EGFR) to block EGFR nuclear translocation. This mode of action alters EGFR-dependent gene transcription, induces the loss of cancer cell survival and migratory capacity, and...
Published: 3/12/2024
|
Inventor(s): Joyce Schroeder, Angelica Escoto, Benjamin Atwell
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics
|
|
Peptide Therapeutic for Triple Negative Breast Cancer
This invention provides compositions and methods for treating breast cancer using peptides or peptide mimics that bind to epidermal growth factor receptor (EGFR) and block transport of EGFR to cell nuclei. This mode of action results in loss of cancer cell survival and migratory capacity and induces tumor regression. This therapeutic induces cell death...
Published: 3/12/2024
|
Inventor(s): Joyce Schroeder, Benjamin Atwell
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics
|
