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Cholesterol-modified Sphingomyelin Lipid Bilayer for Drug and Gene Delivery

This invention is a new type of lipid vesicle or liposome that can be used to encapsulate drugs and genes for therapeutic applications. It improves upon existing liposome formulations in its increased stability, subsequent increased circulation time, and effectiveness as a nanocarrier. Background: For many years, therapeutic drugs were released...

Published: 7/24/2024 | Inventor(s): Jianqin Lu, Zhiren Wang, Wenpan Li

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Healthcare Portfolios > Oncology

Sphyingolipid-Derived Cancer Nanotherapeutics

This invention is an improvement to a commonly used drug delivery vehicle: liposomes. Liposomes, while useful for their improved pharmacokinetics, have not demonstrated significantly improved efficacy and patient survival. This may be in part due to the fact that generally only one drug can be loaded per liposome. However, this technology allows co-delivery...

Published: 11/16/2023 | Inventor(s): Jianqin Lu

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology