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Discovery of Novel DYRK1A Inhibitors
DYRK1A has been implicated in multiple disease states, including Alzheimer's Disease and Down Syndrome. Researchers have discovered a new chemotype that has been exemplified with significant DYRK1A activity and have developed brain-penetrant small molecule DYRK1A inhibitors toward Alzheimer's and the cognitive deficits of Down Syndrome. Future...
Published: 1/10/2024
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Inventor(s): Christopher Hulme, Timothy Chavez, Nathan Bedard
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules
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