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Analytical Technology for the Isolation of 3-Nitrotyrosine as a Biomarker from Urine to Assess Depression and Acute Kidney Injury
This invention uses a novel separation technique to isolate specific biomarkers from urine, as a measure to detect and monitor depression and acute kidney injury (AKI). The system employs a hybrid chromatographic matrix that rejects biomolecules of specific sizes and allows only the desired small compounds, such as 3-nitrotyrosine (which has been linked...
Published: 1/6/2026
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Inventor(s): Roberto Guzman, David Mier-Salazar
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Nephrology/Renal, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
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A Novel Chemical Entity, Mary1, for the Treatment Mitochondrial Dysfunction, Vascular Injury, Kidney Diseases, and Organ Aging
This invention is a novel compound that can be used as a treatment for Acute Kidney Injury (AKI). This new method utilizes a small molecule agonist, capable of increasing mitochondrial biogenesis, which helps restore mitochondrial homeostasis and improves renal function and recovery. The compound showed beneficial effect in mouse model experiments.
Background:...
Published: 1/20/2026
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Inventor(s): Rick Schnellmann, Paul Victor Santiago Raj
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Nephrology/Renal, Technology Classifications > Life Sciences > Small Molecules
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Method, System and Device for Water Conservation and Dialysate Recycling
The technology is a method to recycle water that is used during dialysis. By using activated charcoal, urease, zirconium oxide and zirconium phosphate to filter the water of contaminants, this method can make water achieve a purity level that is acceptable for clinical reuse.
As dialysis becomes an essential treatment for an increasing number of patients...
Published: 1/16/2024
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Inventor(s): Marvin Slepian, Isabel Beeley, Greyson St Pierre, Sophia Qamar, Shane Klemish
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Nephrology/Renal, Technology Classifications > Medical Devices > Therapeutic
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