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HLA-C Single Chain Trimers to Prevent Natural Killer Cell-Mediated Rejection
This invention is for a method of genetic modification of major histocompatibility complex (MCH) component for prevention of natural killer (NK) cell recognition of pluripotent stem cell grafts using HLA-C trimers. This new method works to overcome immunological rejection by the recipient via genetic modification of these cells.
Background:
As of...
Published: 1/21/2025
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Inventor(s): Deepta Bhattacharya, Hannah Pizzato
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Life Sciences > Therapeutics
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