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Method for 3D Nonlinear Structured Illumination Super-resolution Imaging

Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...

Published: 4/3/2023 | Inventor(s): Leilei Peng, Yu Li, Han Zhang

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

Automated Lipid Exchange-Mass Spectrometry System

This invention is an automated label-free method to measure the affinity of membrane proteins for lipids by using conventional small molecule mass spectrometry (MS) to monitor lipid exchange between lipoprotein nanoparticles called nanodiscs. We call this method lipid exchange-mass spectrometry (LX-MS). The concept is that if a membrane protein binds...

Published: 3/12/2024 | Inventor(s): Michael Marty, James Keener, Guozhi Zhang

Keywords(s):

Category(s): Technology Classifications > Research Tools > Protein