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Reversible Crosslinking to Preserve Cell-Specific Gene Expression Across Biospheres
This invention includes chemical methods and reagents to reversibly immobilize the cellular state of gene expression in the field followed by the release of the immobilization in the laboratory for analysis of the gene expression state. Support for this invention was provided by CALS via the Hatch allocation.
Background:
Characterization of single-cell...
Published: 4/3/2023
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Inventor(s): David Galbraith
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays
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Flow Cytometric Disease Diagnostics Based On Biopsies
This invention encompasses cellular analysis at the nucleus-level in order to diagnose diseases. This level of detail has wide application across eukaryotic species.
Background:
While single cell analysis is gaining popularity as well as research and development funding, this invention lends itself to more detailed discovery while being technically...
Published: 4/3/2023
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Inventor(s): David Galbraith
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diagnostics
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Method for Classification of Cells Based on Gene Expression
Researchers at the University of Arizona have developed methodology to characterize global gene expression within a single cell nucleus. It is envisioned that this technology will be applicable to the diagnosis of disease states in tissue or organ biopsies. It will provide signature expression patterns of normal and diseased tissue. A comprehensive...
Published: 4/3/2023
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Inventor(s): David Galbraith, Georgina Lambert, Roger Lasken, Rashel Grindberg
Keywords(s): cancer, diagnosis, gene expression, nucleus, prognosis
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diagnostics
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