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This invention is a small molecule mosquitocide and method of mosquito control is based on selectively inhibiting the blood feeding of female mosquitoes. The compound inhibits nutrient processing and is lethal as shown in adult mosquito assays. Background: Numerous diseases are spread by mosquitoes, which develop resistance to chemical pesticides...

Published: 3/12/2024 | Inventor(s): Jon Njardarson, Jun Isoe, Roger Miesfeld

Keywords(s): biology, molecular

Category(s): Technology Classifications > Veterinary Medicine

Ultra-High Sensitivity Viral Genome Sequencing

University of Arizona researchers have developed a novel process for rapid genome sequencing of RNA-DNA fragments, even those in archived or damaged biological samples. The process utilizes large panels of primers to amplify short RNA-DNA fragments into separate and off-set pools. These off-set pools of amplicons are used to reconstruct whole and near-whole...

Published: 3/12/2024 | Inventor(s): Michael Worobey, Thomas Watts

Keywords(s): biology

Category(s): Technology Classifications > Life Sciences > RNAi/siRNA

Synthesis of Chiral 3-Pyrrolines via an Anionic Annulation Approach

Invention consists of a novel method to access chiral 3-pyrroline products in one step. The treatment of a gamma leaving group with a strong base results in an anion. That anion can then be intercepted by an Ellman type imine. The end result is a robust, reliable, and versatile method to create 3-pyrroline. There are seven main types of anti-hypertensives...

Published: 7/11/2024 | Inventor(s): Jon Njardarson, Isaac Chogii

Keywords(s): biology

Category(s): Technology Classifications > Materials > Chemicals