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Mechanism of Tissue Regeneration
This invention is a biodegradable patch seeded with human neonatal dermal fibroblasts and human induced pluripotent stem cell derived cardiomyocytes which helps regenerate endogenous cardiomyocytes in adult murine, rat, and swine models of myocardial infarction as a cause of chronic heart failure (CHF). This invention details changes in specific gene...
Published: 5/24/2023
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Inventor(s): Steven Goldman, Jennifer Koevary, Jordan Lancaster, Jordan Fink, Adrian Grijalva
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Regenerative Medicine / Tissue Engineering, Technology Classifications > Life Sciences > Therapeutics
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Clinical ECG Parameters from a Bioengineered Human Cardiac Tissue
This technology consists of a bioengineered cardiac tissue that exhibits electrocardiogram parameters and can be used in screening cardiotoxicity and proarrhythmic potential.
Background:
Currently, pharmaceutical compounds must be screened for cardiotoxicity using in vitro testing and animal models. However, current cell-based methods rely on cell...
Published: 4/3/2023
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Inventor(s): Ikeotunye Chinyere, Jordan Lancaster, Jennifer Koevary, Steven Goldman
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Materials > Biomaterials
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Cell Based Therapies for Arrhythmias
This invention is a tissue engineered cardiac patch, which improves left ventricular function. The patch is made from microscopic thin fibers that serve as a scaffold for cells to adhere to.
Applications:
Pharmaceutical industry
Biotechnology and medical device companies
Hospitals
Surgical centers
Research laboratories
Advantages:
Novel...
Published: 8/28/2023
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Inventor(s): Jordan Lancaster, Steven Goldman, Jennifer Koevary, Ikeotunye Chinyere
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Therapeutics
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Cardiac Electrophysiologic Mapping and Stimulation Software
This invention is patented software developed for MATLAB capable of performing electrophysiological studies with human disease models.
Background:
Simulation studies aid with the advancement of cardiovascular research by complementing experimental studies. Current technologies have not utilized a proper recording method in their software. The software...
Published: 4/3/2023
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Inventor(s): Ikeotunye Chinyere, Kyle Weigand, Russell Witte, Steven Goldman, Talal Moukabary, Mathew Hutchinson, Jennifer Koevary, Jordan Lancaster
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology, Technology Classifications > Software & Information Technology > Bioinformatics
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Graphical User Interface for Electrophysiology Studies in Small Animals
This technology presents a Graphical User Interface (GUI) in conjunction with software written for recording and storing signals related to electrophysiological studies. Once recorded, this data can be filtered, extracted, and mapped, in color, to visualize properties. Developed along with corresponding techniques used in rat electrophysiology studies,...
Published: 6/26/2023
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Inventor(s): Kyle Weigand, Russell Witte, Steven Goldman
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Diagnostic
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