Invention:
This invention allows for the collection of real-time chemical analysis of neurotransmitters in the brains of lab animals via rapid application of voltage with resulting current measurement from microelectrodes. Tiny carbon-fiber electrodes are implanted into the animal, and electrochemical measurements are recorded, providing information to relate concentrations of neurotransmitters in the brain to behavior of the animal.
Background:
Understanding the complex functions of a brain remains one of the grand challenges of biomedical research. One possible way is to develop in vivo biosensors for monitoring the activities and the signal pathways of neurotransmitters in the brain. Neurotransmitters are essential chemicals that can transfer information between the neuron cells. Hence, monitoring the concentrations of various neurotransmitters is of great importance in assessing brain function. A biochemical sensor that can continuously monitor the dynamic behaviors of the various neurotransmitters in real-time can be a powerful tool for monitoring and treating patients with neurological brain disorders.
Applications:
- Biomedical research
- Bioengineering
- Neurology
Advantages:
- In vivo brain neurotransmitter analysis
- Collects and analyzes data in real-time
