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CLEO-AI: Closed-Loop Edge System for Optimized and Adaptive Intelligence
CLEO-AI is a closed-loop edge artificial intelligence framework that allows resource-limited devices to learn, optimize, and redeploy models in real time without cloud dependence. It combines on-device model growth, training-free compression, and a hardware-agnostic runtime, enabling systems-on-chip (SoCs) to adapt to changing data or environments while...
Published: 1/6/2026
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Inventor(s): Ali Akoglu, Mustafa Ghanim, Saul Durazo Martinez, Md Sahil Hassan
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Electronics
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High Resolution 3D Imaging of Diamonds with Multiphoton Microscopy
This invention describes a method of using multiphoton microscopy (MPM) for 3-dimensional imaging and spectral analysis of natural and synthetic diamonds, as well as diamond-like simulants. This non-destructive approach provides insights into the interior structure, fluorescent defects, and formation conditions of diamonds. This method can be used to...
Published: 1/6/2026
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Inventor(s): Khanh Kieu, Elana Alevy, Sam Crossley, Lam Nguyen, Phai Vu
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Imaging & Optics > Sensors and Detection > Inspection
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Morphable Multicopter UAS (MMU)
This technology is a morphable multicopter uncrewed aerial system (UAS) or “MMU.” The MMU consists of a link-joint structure connecting powered cells (with rotors) and unpowered cells carrying payloads. The structure can safely change shape, deforming to navigate narrow spaces. The MMU is equipped with precise cell location control enabling...
Published: 1/6/2026
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Inventor(s): Hossein Rastgoftar
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Aerospace Engineering
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Isolation and Separation of Angiotensin I and II from Human Serum Using a New Chromatographic Matrix that Excludes High Molecular Weight Proteins
This innovation introduces a novel chromatographic matrix that effectively isolates and separates angiotensin I and II, key biomarkers involved in blood pressure regulation, from human serum. The system uses a hybrid combination matrix that selectively removes small molecular weight polypeptides while excluding large serum proteins. By integrating chelating...
Published: 1/6/2026
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Inventor(s): Roberto Guzman, David Mier-Salazar, Daniel Alejandro Diaz
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease, Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
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Analytical Technology for the Isolation of 3-Nitrotyrosine as a Biomarker from Urine to Assess Depression and Acute Kidney Injury
This invention uses a novel separation technique to isolate specific biomarkers from urine, as a measure to detect and monitor depression and acute kidney injury (AKI). The system employs a hybrid chromatographic matrix that rejects biomolecules of specific sizes and allows only the desired small compounds, such as 3-nitrotyrosine (which has been linked...
Published: 1/6/2026
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Inventor(s): Roberto Guzman, David Mier-Salazar
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Nephrology/Renal, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
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Therapeutic Target of Ewing Sarcoma by G-Quadruplex Binding Compound
This innovation identified lead molecules that target specific nucleic acid structures involved with forming G-Quadruplex structures. These G-Quadruplex structures are a highly stable nucleic acid fold with planar stacks of guanine tetrads which regulate genome stability, transcription, and telomere maintenance. This innovation details a therapeutic...
Published: 1/6/2026
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Inventor(s): Jacob Schwartz, Haining Zhu, Ajibola Adelekun, Valery Thompson
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology
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Novel Therapy for Ischemic and Pressure-Overload Heart Diseases
This novel therapy involves using valosin-containing protein (VCP) to prevent or treat ischemic and pressure overload-induced heart disease. Inactivation and reduced VCP expression are highly associated with multiple cardiac diseases. Overexpression of VCP in the heart has been found to reduce infarct size during ischemia-reperfusion injury and also...
Published: 12/12/2025
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Inventor(s): Hongyu Qiu
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Therapeutics
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Intelligent Solar Window Frame (ISoW Frame aka JoMactt Window) for Buildings on the Earth, Moon, Mars and Beyond
The JoMactt Window is an intelligent solar window solution made up of many individual laminated glass units, each one containing multiple retractable quantum dot layers. Each unit has different quantum dot densities and transparencies that can be altered to vary the unit’s solar electricity conversion efficiency. Only one of the glass units in...
Published: 12/8/2025
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Inventor(s): Joel Cuello, Mackenze McAleer, Matteo Pietrobelli
Keywords(s):
Category(s): Technology Classifications > Energy, Cleantech & Environmental > Renewable Energy > Solar/Photovoltaic
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Adaptive Spatial Mode Correction for Free-Space Optical Communication Without Reference Beams
This invention provides a guide-star-free adaptive correction method for free-space optical (FSO) communication links. The system employs a high-speed spatial light modulator or equivalent adaptive optical element to detect and correct turbulence-induced distortions directly from the communication signal. By continuously optimizing a signal-quality...
Published: 12/23/2025
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Inventor(s): Mohamed ElKabbash
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Communications & Networking > Optical, Technology Classifications > Imaging & Optics > Telecommunications, Technology Classifications > Imaging & Optics > Data Storage
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Radiation-Hardened Nanophotonic Thermal Emitters with Spectral and Angular Selectivity for Spaceborne Radiative Cooling
This technology introduces a radiation-hardened nanophotonic surface engineered for high-efficiency radiative cooling in low Earth orbit (LEO). The metasurface employs angular and spectral selectivity to maximize emission toward deep space while minimizing absorption of sunlight and planetary infrared radiation. Constructed from refractory and ceramic...
Published: 12/8/2025
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Inventor(s): Mohamed ElKabbash
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Aerospace Engineering, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Semiconductors, Technology Classifications > Engineering & Physical Sciences > Quantum, Technology Classifications > Imaging & Optics > Data Storage, Technology Classifications > Engineering & Physical Sciences > MEMS & Nanotechnology
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