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Human-Governed Control of Digital Thread Data
This innovation introduces a novel methodology for Digital Engineering wherein data is aggregated rather than propagated and provided to a human engineering manager for decision making purposes. Unlike the current paradigm, this approach aims to consolidate information without automatically disseminating it across models, providing a more effective...
Published: 12/2/2025
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Inventor(s): Alejandro Salado
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Computer-Aided Design & Engineering, Technology Classifications > Software & Information Technology
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Multi Polish Robot Polishing Method
This invention is for a robotic system that is designed to polish multiple regions of a large optical surface simultaneously. It includes a novel internal propulsion mechanism that uses coils to drive a magnetic weight along a circular track. This method can accelerate the mirror fabrication time, eliminating the need for off-line testing, reducing...
Published: 12/1/2025
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Inventor(s): Heejoo Choi, Kevin Derby, Casey Scoggins, Hyukmo Kang, Vipender Negi, Daewook Kim, Maxim Duque, Chaemin Lee
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Optical Fab / Metrology, Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Robotics
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A Flexible, Scalable Platform Technology to Augment Antibiotic Efficacy
This invention relates to a novel, safe, and efficacious approach to reduce antibiotic concentrations required to kill pathogenic bacteria. The product thus augments antibiotic efficacy, including against bacteria that are clinically resistant.
Background:
One of the biggest risks to global public health is antibiotic resistance. Through processes...
Published: 12/1/2025
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Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan, Arun Sharma, David Stewart
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics
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Nanoscale Scanning Thermal Microscopy using Improved Thermocouple Probes
This technology is a scanning thermal microscope device. It utilizes a thermocouple with a sharp tip on its center fabricated from a cross-junction of coated and uncoated thin films and is suspended on a nanowire device. Radiation heat received at the tip is converted into a Seeback voltage signal for thermoelectric temperature sensing. This device...
Published: 11/24/2025
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Inventor(s): Qing Hao, Christopher Horne, Liping Wang
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Sensors & Controls, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
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AHPND Detection using Monoclonal Antibodies (mAbs)
Monoclonal antibodies (mAbs) with strong and specific immunoreactivity have been developed to improve the detection of acute hepatopancreatic necrosis disease (AHPND) in marine shrimp. This involves cloning and expressing recombinant PirA and PirB protein using a bacterial expression system and developing mAbs against those proteins. These monoclonal...
Published: 11/24/2025
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Inventor(s): Arun Dhar, Nam Hung Mai
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture, Technology Classifications > Life Sciences > Diagnostics
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Isolation of Protein Biomarkers from Saliva as a Technology to Assess and Monitor Cardiac Infarction
This technology introduces a novel separation method designed to isolate small protein biomarkers directly from saliva, enabling a rapid and non-invasive diagnostic approach for cardiac infarction. The system employs a hybrid chromatographic matrix that selectively rejects large proteins while allowing smaller biomarkers to interact with affinity sites...
Published: 11/24/2025
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Inventor(s): Roberto Guzman, David Mier-Salazar, Christopher Rodriguez
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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Novel Mechanism-Based Therapy for Aortic Stiffening and Related Cardiovascular and Cerebrovascular Disorders
This invention involves a novel mechanism-based therapy by using a small molecule compound to reduce aging and hypertensive aortic stiffening, subsequently improve blood pressure (BP) control in resistant hypertension patients and prevent or reverse pathologies of vascular cognitive impairment and dementia (VCID) and Alzheimer’s Disease (AD)....
Published: 11/24/2025
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Inventor(s): Hongyu Qiu
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
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Repurposing the FDA-Approved Antibody to Treat Aortic Stiffening and Resistant Hypertension
This innovation repurposes an FDA-approved antibody to treat and prevent aortic stiffening and resistant hypertension (RH). This mechanism-based therapeutic, inhibits receptor mediated inflammatory and pro-stiffness signaling to reduce aortic stiffness and improve blood pressure control, ultimately breaking the root cycle of hypertension.
Background:...
Published: 11/24/2025
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Inventor(s): Hongyu Qiu
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Therapeutics
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Ultra Black and Ultra White Coating on Different Sides of a Wind Turbine Blade to have Additional Energy from Solar
This invention aims to improve the efficiency and power output of wind turbines using additional energy from sunlight. The pressure side of each wind turbine blade is coated ultra black, and the suction side of each wind turbine blade is coated ultra white. When sunlight shines on the turbine, these coatings cause the light to contribute to the rotational...
Published: 11/13/2025
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Inventor(s): Peiwen Li
Keywords(s):
Category(s): Technology Classifications > Energy, Cleantech & Environmental > Renewable Energy > Wind, Technology Classifications > Energy, Cleantech & Environmental > Renewable Energy, Technology Classifications > Materials > Coatings
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Interface Profilometry with Third Harmonic Generation Microscopy
This invention describes a method of third harmonic-generation (THG) multiphoton microscopy for interface profilometry with depth resolution at the nanometer scale. While the axial resolution of the system is on the scale of micrometers, this invention can precisely define the peak of a THG depth response curve, or how intensity varies as a function...
Published: 11/10/2025
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Inventor(s): Khanh Kieu
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Materials & Fabrication, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Sensors and Detection
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