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Compounds as TDP-43 LLPS Modulators
This technology provides compounds and pharmaceutical compositions comprising small molecules that inhibit the formation of TAR DNA-binding protein 43 (TDP-43) condensates, which are protein aggregates linked to various neurodegenerative diseases including Alzheimer’s disease. By suppressing the formation of these aggregates, these molecules improve...
Published: 2/19/2024
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Inventor(s): Xinglong Wang
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences
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