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TDP-43 In Vivo Mouse Model
This is an in vivo mouse model of TDP-43 proteinopathy that captures key features of human neurodegenerative disease, particularly Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD). The model targets a disease-relevant disruption in TDP-43’s interaction with cytoplasmic translational machinery, causing a cascade...
Published: 9/2/2025
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Inventor(s): Xinglong Wang, Ju Gao
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Research Tools > Animal Models
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