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DNA as an Antimicrobial Agent for Preventing Neisseria Gonorrhoeae Infection
This invention encompasses a series of DNA-based antimicrobial compounds that prevent transmission of Neisseria gonorrhoeae (Ngo) during sexual intercourse and possibly treat an extant Ngo infection, alone or in combination with antibiotics, while leaving commensals unharmed. These DNA molecules are effective against low-passage antibiotic sensitive...
Published: 9/25/2024
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Inventor(s): Maria Rendon, Magdalene So
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Use of DNA Containing Specific Sequences to Prevent Neisseria Gonorrhoeae Infection
This invention encompasses an antimicrobial that can treat disease caused by the pathogen Neisseria Gonorrhoeae (Ngo). The compounds described can be incorporated into commercially available personal lubricants for individual use.
Background:
N. gonorrhoeae (Ngo) causes over 160 million new cases of gonorrhea each year globally; in 2018, it caused...
Published: 4/3/2023
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Inventor(s): Magdalene So, Maria Rendon
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Genes and Polypeptides of Neisseria Musculi that can be used to Evaluate Vaccines and Anti-Bacterial Compounds against Infection by Pathogenic Neisseria Species
A set of Neisseria musculi (Nmus) genes have been identified which promote Nmus infection and persistence in its natural host, the mouse. These genes have never been described before, so the in-host function of their encoded proteins is unknown. These genes are present in the human pathogenic Neisseria, N. meningitidis and N. gonorrhoeae. These genes...
Published: 4/3/2023
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Inventor(s): Magdalene So, Katherine Rhodes, Maria Rendon
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics
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Treatment of Gonorrhea
This patented technology is a method of treatment for gonorrhea that involves the use of a commensal, non-pathogenic microorganism that antagonizes and kills the bacterium responsible for causing gonorrhea.
Background:
The CDC estimates that over 700,000 gonorrhea infections occur annually in the US alone. European officials have estimated that...
Published: 10/1/2024
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Inventor(s): Magdalene So, Maira Goytia, Ann Jerse, Dustin Higashi, Won Jong Kim, Maria Rendon
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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