A Mitochondria-Focused Mouse Model (DRP-1-/- mouse) to Accelerate Gastrointestinal Pathophysiology Research
This invention is a transgenic DRP-1-/- mouse model that will help address the central role of mitochondrial structure-function dynamics in the mammalian intestine. This mouse model harbors an intestine-specific disruption in DRP-1, a key mitochondrial membrane-associated protein, which will be useful in assessing how mitochondrial structure/interaction...
Published: 9/12/2024
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Inventor(s): Virinchipuram Viswanathan, Gayatri Vedantam, Jean Wilson, Jennifer Lising
Keywords(s):
Category(s): Technology Classifications > Research Tools > Animal Models
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A Mitochondria-Focused Mouse Model (OPA-1-/- mouse) to Accelerate Gastrointestinal Pathophysiology Research
The invention is two engineered OPA-1-/- mouse models that will help address the central role of mitochondrial structure-function dynamics in the mammalian intestine – a translationally critical, but extremely underdeveloped, resource. This mouse models harbor an intestine-specific disruption in OPA-1, a key mitochondrial membrane-associated protein,...
Published: 5/20/2024
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Inventor(s): Virinchipuram Viswanathan, Gayatri Vedantam, Jean Wilson, Jennifer Lising
Keywords(s):
Category(s): Technology Classifications > Research Tools > Animal Models
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Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
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Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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All-Fiber Multicore Fiber Laser Devices
Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...
Published: 4/3/2023
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Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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