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A Mitochondria-Focused Mouse Model (OPA-1-/- mouse) to Accelerate Gastrointestinal Pathophysiology Research
The invention is two engineered OPA-1-/- mouse models that will help address the central role of mitochondrial structure-function dynamics in the mammalian intestine – a translationally critical, but extremely underdeveloped, resource. This mouse models harbor an intestine-specific disruption in OPA-1, a key mitochondrial membrane-associated protein,...
Published: 3/18/2024
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Inventor(s): Virinchipuram Viswanathan, Gayatri Vedantam, Jean Wilson, Jennifer Lising
Keywords(s):
Category(s): Technology Classifications > Research Tools > Animal Models
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