Invention:
Herbostroiodine is an innovative herbal extended release radioprotective drug formulated with a multilayer noisome carrier. Its composition includes natural products. The use of noisome as a carrier enhances oral bioavailability and allows for the simultaneous delivery of both hydrophobic and hydrophilic agents. Herbostroiodine exhibits dual-action by chelating and removing radioactive elements like I-131 and Sr90 from the body while mitigating their adverse effects. It surpasses conventional radioprotective drugs, such as potassium-iodine, in effectiveness and safety, with minimal side effects. Inspired by the resilience of cockroaches and bdelloid rotifers to radiation, this herbal drug offers a novel approach to radiation protection and has potential applications in anti-cancer, anti-inflammatory, and antioxidant therapies.
Background:
The development of Herbostroiodine stems from the need for a more effective and safer radioprotective drug in the face of radioactive elements like I-131 and Sr90, which pose significant health risks. Traditional remedies often have limited efficacy and undesirable side effects. The innovation lies in its unique formulation using noisomes, enabling the simultaneous delivery of hydrophobic and hydrophilic agents for enhanced oral bioavailability. Additionally, the inclusion of natural products in specific concentrations imparts high radioprotective and antioxidant properties, offering a therapeutic index superior to existing options. This invention not only addresses the urgent need for better radioprotection but also draws inspiration from nature’s radiation-resistant creatures to optimize its mechanism of action.
Applications:
- Radioprotective drug
- Anti-cancer drug (specifically bone and thyroid cancers)
- Anti-inflammation / antioxidant drug
Advantages:
- Enhanced efficiency
- Minimal side effects
- Novel formulation with enhanced absorption characteristics
- Increased oral bioavailability
- Dual action: chelation and removal of I-131 and Sr90 radioactive elements and recovery from adverse effects
