Invention:
University of Arizona researchers have developed a novel, one-step, catalyst-free, and solvent-free synthetic process for the nitration of aromatic compounds. This method has been used to prepare 2,4-dinitroanisole, an alternative to trinitrotoluene (TNT), as an ingredient in melt-cast explosive formulations; and dinitrophenyl ethers. This synthetic process can be utilized to produce a variety of nitroaromatic compounds in a fast, straightforward, and more economical fashion than traditional chemical methods.
Background:
Traditional synthetic nitration methods often employ catalysts, solvents, or other additives that are harmful to the environment and/or expensive. This synthetic process overcomes these issues by allowing the nitration of various aromatic compounds in a catalyst-free and solvent-free fashion.
Applications:
- Explosives for mining, construction or military purposes
- Metabolic disease therapeutics
- Fermentation process aid
- Herbicides
Advantages:
- Requires only one step
- Maintains a highly selective process
- Does not require the use of a solvent, therefore reducing cost
- Does not require the use of expensive, harsh, or toxic catalysts
- Exhibits increased efficiency over other reported methodologies
- Retains a broad reaction scope
