Rapid Partial-Measurement Mueller Matrix Imaging of the In Vivo Human Eye

Case ID:
UA26-098
Invention:

This invention describes a method of creating a full Mueller matrix of the eye with fewer than 16 polarization measurements. This partial measurement approach reduces the overall data acquisition time, an important advantage considering the rapid temporal variations of the eye.

Background: 
Being able to accurately assess the optical properties of the human eye is essential for diagnosing corneal disorders and monitoring eye disease progression. Many structures in the anterior segment of the eye exhibit polarization-dependent behavior that traditional imaging systems cannot capture. Existing systems that do offer insight into the polarization-dependent tissue of the eye tend to be slow, complex, and sensitive to motion. There is a need for an imaging approach that can capture meaningful polarization information rapidly while also being compatible with real-world patient motion.

Applications: 

  • Ophthalmic imaging
  • Clinical diagnostics
  • Surgical planning and guidance
  • Research and clinical trials


Advantages: 

  • Early detection of corneal diseases
  • Cataract characterization
  • Ocular surface assessment
  • Reduces acquisition time
Patent Information:
Contact For More Information:
Richard Weite
Senior Licensing Manager, College of Optical Sciences
The University of Arizona
RichardW@tla.arizona.edu
Lead Inventor(s):
Meredith Kupinski
Keywords: