Photonic DNA Sequencing using Graphene Nanopores

Case ID:
UA25-006
Invention:

This invention pertains to a novel method for DNA sequencing utilizing graphene nanopores and photonic detection to achieve high-resolution base detection. By combining graphene, which has exceptional electrical and mechanical properties that enable high-resolution base detection, with light-based detection that can use multiple wavelengths to simultaneously to detect different base pairs, this method achieves high-resolution, rapid, and accurate DNA sequencing.

Background: 
DNA sequencing is important for understanding genetic information, identifying diseases, developing treatments, and creating personalized medicine. Traditional methods, such as those that monitor electrical signals through nanopores, may have lower accuracy due to the rapid movement of DNA strands. This new method uses graphene and photonic detection to overcome these limitations, making DNA sequencing faster and more precise than current methods.

Applications: 

  • DNA sequencing 
  • Genomics
  • Epigenetics
  • Medical diagnostics 
  • Personalized medicine 
  • Biotechnology 
  • Forensic DNA analysis


Advantages: 

  • High resolution 
  • Faster readouts with photonic detection
  • Better sensitivity 
  • More accurate
Patent Information:
Contact For More Information:
Richard Weite
Senior Licensing Manager, College of Optical Sciences
The University of Arizona
RichardW@tla.arizona.edu
Lead Inventor(s):
Mohamed ElKabbash
Keywords: