Invention:
Inventors at the University of Arizona have discovered compounds that have a potent larvicidal effect on Anopheles stephensi and a moderate larvicidal effect on Aedes aegypti. The synthesis can be done in only a few steps and the compounds show a high degree of chemical specificity.
Background:
Numerous diseases are spread by mosquitoes including Dengue virus, a mosquito-borne virus that infects roughly 250 million humans per year. Larviciding can be an effective strategy of Integrated Pest Management (IPM) where mosquito larvae are terminated before reaching maturation.
Applications:
- Mosquitocides
- Larvicides
- Global health
- Agriculture
Advantages:
- Results in high mosquito larvae mortality rates
- Provides a high degree of chemical specificity
- Requires only a few steps
- Mild reaction conditions and high yields
- Results in minimal impact on the environment
