Invention:
This invention involves a type of medical tube/tubing or catheter with a glycocalyx mimetic coating to prevent blood clotting.
Background:
The endothelial glycocalyx is a dynamic surface layer of vascular endothelial cells, of vascular endothelial cells, acting as a critical, multi-functional barrier for vascular health. It maintains vascular homeostasis by regulating permeability, mechanosensing, and preventing blood cell adhesion (preventing thrombosis and inflammation). Currently, there is a lack of available and reliable glycocalyx-mimetic coatings on vascular devices, such as with catheters or medical device tubing. This invention adds glycocalyx mimetics as a coating layer on medical tubing to replicate glycocalyx functionality for better compatibility and usage of medical devices.
Applications:
- Glycocalyx mimetics
- Catheter device
- Medical tubing devices
- Vascular tubing devices
- Surgical and critical care
Advantages:
- Blood clotting prevention and hemocompatibility
- Better implementation of medical devices
- Reduced cardiovascular disease
- Decreased inflammation
- Medical tube coating market expansion
- Reduced complications from surgical and critical care procedure including pulmonary embolism and stroke
