Invention:
This invention introduces a compact multimodal imaging probe that integrates high-resolution imaging modalities, such as confocal and multiphoton imaging, alongside widefield reflectance or fluorescence imaging. Unlike traditional methods that use a beamsplitter or dichroic mirror to combine the modalities, this approach places the imaging components side by side, reducing size while maintaining functionality. By carefully cutting away a small portion of the high-resolution system, space is created for the widefield imaging system without significantly impacting light efficiency. This design offers a streamlined solution for clinical imaging applications where space is limited, making it easier to gather comprehensive information about tissue conditions. The system is designed to balance high precision and wide coverage, making it an effective tool for medical diagnostics and other clinical applications.
Background:
Multimodal imaging systems are crucial for applications in biomedical diagnostics, material analysis, and scientific research, where both high-resolution detail and broader field context are needed. The problem this technology addresses is the challenge of combining high-resolution and widefield imaging modalities in a compact and efficient system for clinical applications. Current solutions often rely on using beamsplitters or dichroic mirrors to integrate these modalities, which can increase the size of the device and limit its practical use in confined spaces. Additionally, current systems may suffer from light loss and reduced imaging efficiency due to the complexity of combining these technologies. This invention addresses these limitations by introducing an offset optical axis for the widefield imaging system, allowing alignment with high-resolution imaging regions while keeping the device compact. This design is more space-efficient and overcomes limitations related to device size, making it a better option for clinical environments where precision and compactness are crucial.
Applications:
- Medical diagnostics
- Tissue imaging in clinical settings
- Biomedical research
- Optical metrology
Advantages:
- Compact design allows for use in confined spaces
- Reduced light loss compared to traditional beamsplitter designs
- High-resolution and widefield imaging in a single system
- Alignment precision
