Invention:
This innovation is a novel method of synthesizing calcium channel blockers, with applications to extend the half-life of heart disease medications. This can be used as building blocks to create new pharmaceuticals or potentially used to expand the lifespan of current medications. It has applications to site specific calcium-channel blocking that can increase the duration of protection provided to the arteries and prevent calcium from damaging them.
Background:
There has been a growing need for deuterated molecules, as they have begun playing an increased role in inhibiting certain metabolic processes. Current calcium-channel blocking pharmaceuticals have relatively short half-lives in the body. The fallout from the COVID-19 pandemic led to an increase in patients with various heart diseases and intensified many of the symptoms of those who were already diagnosed. This has led to doctors and patients seeking improved solutions.
Applications:
- Calcium-channel blocking pharmaceuticals
- Heart disease medications
- Pharmaceutical compound synthesis
Advantages:
- Cost-effective
- Simplified synthesis
- Durable chemical bonds
- Increased half-life of medications
