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Photocatalytic Alpha Arylation of Carbonyls

This invention is a method for the synthesis of alpha arylation of inexpensive, unactivated carbonyl compounds with high yields at room temperature using any photocatalyst (PC) under visible light from blue to red. Background: Functionalization of the C-H bond has evolved as a fundamental principle that underpins both academic and industrial importance...

Published: 3/12/2024 | Inventor(s): Thomas Gianetti, Md Mubarak Hossain

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Category(s): Technology Classifications > Materials > Chemicals, Technology Classifications > Materials > Processing, Technology Classifications > Life Sciences > Small Molecules

Photocatalytic Alpha Arylation of Carbonyl at Room Temperature to Simplify and Reduce Costs of Manufacturing Pharmaceuticals

This invention is a new synthesis route for producing an alpha-aryl substituted cyclic ketone from a cyclic ketone compound using an aryl halide and an acridinium ion photocatalyst. The method of the invention is particularly useful in producing an alpha-aryl substituted cyclic ketone from an un-activated cyclic ketone compound. This is vast improvement...

Published: 3/12/2024 | Inventor(s): Thomas Gianetti, Md Mubarak Hossain

Keywords(s):

Category(s): Technology Classifications > Materials > Chemicals