Calibrated In Vivo Blood Oximeter
This invention is a calibrated in vivo blood oximeter that is accurate to 1% SO2. The technology is based on a sensing surface that detects individual red blood cell refractive index. The sensing surface works on the principle of surface Plasmon resonance for individual red blood cells (RBCs), which is insensitive to RBC concentration and size, as well...
Published: 4/3/2023
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Inventor(s): Thomas Milster, Kurt Denninghoff
Keywords(s): intravenous probe, oxygen saturation, plasmon, red blood cell
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics
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Sub-Cellular Imaging and Manipulation via Hyper-Numerical Aperture Imaging Surfaces
High spatial resolution and detection of sub-cellular physiology (like respiration) is achieved using a near-field imaging surface that can be manipulated mechanically inside living biological matter. This new near-field probe is photon efficient, unlike most near-field scanning probes, and is a true imaging probe, not a point source or point collector....
Published: 4/3/2023
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Inventor(s): Thomas Milster, Kurt Denninghoff
Keywords(s): biological imaging, near-field probe, sub-cellular imaging
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics
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Microscopy for the Identification of Oxyhemoglobin Species in Red Blood Cells
This novel invention combines a Solid Immersion Lens (SIL) microscope with the Surface Plasmon Resonance (SPR) effect to achieve precise measurement of refractive index of a target, with high spatial resolution. When used to examine Red Blood Cells (RBC) at multiple wavelengths, the refractive index measurement yields the variation in oxygen content...
Published: 4/3/2023
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Inventor(s): Thomas Milster, Kurt Denninghoff, Pramod Khulbe, Jun Zhang
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics
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