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An Iterative Approach to Polish the Nanopore Sequencing Basecalling for Therapeutic RNA Quality Control
This invention is an improvement of nanopore sequencing base calling accuracy via an iterative approach using existing machine learning algorithms and alignment with ground-truth references. This new method allows base calling accuracy to improve as the technology is trained, which in turn creates countless opportunities for sequencing improvement in...
Published: 5/30/2025
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Inventor(s): Hongxu Ding
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Vaccines, Technology Classifications > Life Sciences > RNAi/siRNA, Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Software & Information Technology > Health IT
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