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Bio-Engineered Human Prostate Disease Model

This invention is an in vitro human prostate disease model that utilizes microfluidic Organ-on-Chip technology. The model comprises multiple compartments separated by porous membranes, allowing for the co-culturing of essential tissue types involved in prostate diseases. It provides a physiologically relevant environment and enables communication among...

Published: 10/4/2023 | Inventor(s): Linan Jiang, Cynthia Miranti

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Category(s): Technology Classifications > Healthcare Portfolios > Urology, Technology Classifications > Research Tools > Simulators and Modeling Tools

G-Quadruplex Targeting Small Molecules for the Treatment of Castration Resistant Prostate Cancer and HSV-1

This technology consists of a new class of small-molecules that target G-quadruplex formation. These compounds have the potential to treat a wide variety of diseases including prostate cancer. In particular, these compounds are aimed at helping individuals who have developed a resistance to androgen-deprivation therapies (ADT). While most ADT therapeutics...

Published: 11/16/2023 | Inventor(s): Elsa Reyes Reyes, Cynthia Miranti, Laurence Hurley, Vijay Gokhale, Kui Wu, Sara Richter

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Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics