Invention:
This innovation is composite filaments for 3D printing bioresorbable scaffolds for surgical implantation. These filaments typically have high strength, an appropriate resorption rate, and high biocompatibility. The resulting scaffolds offer customizable shapes and resorption rates.
The improvement in this innovation compromises a bone volume fraction (BV/TV) of the implanted PBT, PLA, and composite ceramic polymer biomimetic scaffolds. Furthermore, the bone volume (mm3) demonstrates that the composite ceramic scaffolds support more bone growth into the scaffold than pure PBT or PLA.
Background:
Long bone segment defects typically result from extensive bone resection from cancer or severe extremity trauma. In weight-bearing long bones, the bone is often unable to heal properly following surgical reconstruction, and the result is non-union.
These defects are difficult to treat and may require amputation or endoprosthetic replacement. Patients experiencing these defects may undergo multiple surgeries with outcomes of reconstruction and grafting comparable to those of amputation, though neither is optimal.
Applications:
- Orthopedic surgery
- Resorbable bone scaffolds
- 3D printed surgical solutions
- Composite filaments for 3D printing
Advantages:
- High strength
- Customizable shape
- High biocompatibility
- Customizable resorption rate
